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Where DOT regulations ruleĪ specimen with creatinine levels (a waste product in the blood created by the normal use of muscle cells) of greater than or equal to 2 mg/dl but less than 5 mg/dl, and specific gravity less than or equal to 1.0010 calls for the Medical Review Officer (MRO) to require the donor to return for a second collection under direct observation. If the result is a negative dilute, many drug testing policies will require employees to return for another drug test. When it is not part of a federally regulated program, an employer must follow their documented policy for positive results. A positive dilute drug test result occurs when creatinine levels are outside of the normal range and drug metabolites are detected.Ī positive dilute is always considered positive and will result in termination if conducted under a program for federal employees or a DOT drug test. When drug metabolites are not detected, in conjunction with creatinine levels that are out of the normal range, results in a negative dilute drug test result. (Also note that consuming large quantities of fluid will not affect mouth swab or hair follicle drug tests in any way.)Ĭreatinine levels that are out of the normal range may indicate that someone attempted to hide or mask drug use. This is because drug metabolites-the biological byproducts of drug use-will still show up in a test sample, and consuming excess fluids will cause your body’s creatinine levels to be out of the normal range. While that last cup of coffee or glass of water will not adversely affect your urine drug test, consuming large quantities of fluid may, but not in the way that some people believe.ĭespite one of the most common myths about drug testing, flushing your system with excess fluids will not hide or mask drug use. If you’ve ever wondered what the term negative dilute drug test result means, today you’ll get an exact, yet simple answer.